Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 13/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | TOP1 | P11387 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546983 | 1.00 | LMNA (0.57) | LMNAMT-CO2PTGS2TOP1MEN1 | |
| SCHEMBL29047655 | 0.92 | MAPK14 (0.48) | LMNAMT-CO2PTGS2TOP1CYP1A2 | |
| SCHEMBL30546971 | 0.92 | MAPK14 (0.48) | LMNAMT-CO2PTGS2TOP1CYP1A2 | |
| SCHEMBL29047672 | 0.90 | MAPK14 (0.49) | LMNAMT-CO2MAPTMAPK14PTGES | |
| SCHEMBL30546973 | 0.90 | MAPK14 (0.49) | LMNAMT-CO2MAPTMAPK14PTGES | |
| SCHEMBL30546943 | 0.89 | LMNA (0.46) | LMNAMT-CO2PTGS2TOP1MAPT | |
| SCHEMBL29047696 | 0.89 | LMNA (0.46) | LMNAMT-CO2PTGS2TOP1MAPT | |
| SCHEMBL30546938 | 0.86 | TAS2R14 (0.47) | LMNAMEN1MAPTKMT2AMAPK14 | |
| SCHEMBL29047640 | 0.86 | TAS2R14 (0.47) | LMNAMEN1MAPTKMT2AMAPK14 | |
| SCHEMBL28398111 | 0.85 | STIM1 (0.53) | LMNAMEN1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |