Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.44 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546971 | 1.00 | MAPK14 (0.48) | MAPK14LMNARXFP1STIM1ORAI1 | |
| SCHEMBL29047665 | 0.92 | LMNA (0.57) | MAPK14LMNACYP1A2HPGDCYP2C19 | |
| SCHEMBL30546983 | 0.92 | LMNA (0.57) | MAPK14LMNACYP1A2HPGDCYP2C19 | |
| SCHEMBL29047672 | 0.91 | MAPK14 (0.49) | MAPK14LMNARXFP1STIM1ORAI1 | |
| SCHEMBL30546973 | 0.91 | MAPK14 (0.49) | MAPK14LMNARXFP1STIM1ORAI1 | |
| SCHEMBL29047710 | 0.91 | ALOX15 (0.46) | MAPK14LMNARXFP1PDE4BKDM4E | |
| SCHEMBL30546967 | 0.91 | ALOX15 (0.46) | MAPK14LMNARXFP1PDE4BKDM4E | |
| SCHEMBL28398111 | 0.88 | STIM1 (0.53) | MAPK14LMNARXFP1STIM1ORAI1 | |
| SCHEMBL29047585 | 0.88 | FTO (0.44) | MAPK14LMNARXFP1STIM1ORAI1 | |
| SCHEMBL29047686 | 0.88 | LMNA (0.49) | MAPK14LMNARXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |