Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546938 | 1.00 | TAS2R14 (0.47) | TAS2R14MAPTGBA1POLBKDM4E | |
| SCHEMBL29047697 | 0.93 | MAPT (0.44) | TAS2R14MAPTKDM4ERAB9ALMNA | |
| SCHEMBL30546926 | 0.93 | MAPT (0.44) | TAS2R14MAPTKDM4ERAB9ALMNA | |
| SCHEMBL29047646 | 0.89 | RAB9A (0.47) | MAPTKDM4ERAB9ALMNANPC1 | |
| SCHEMBL30546924 | 0.89 | RAB9A (0.47) | MAPTKDM4ERAB9ALMNANPC1 | |
| SCHEMBL30546928 | 0.89 | TAS2R14 (0.47) | TAS2R14MAPTPOLBKDM4ERAB9A | |
| SCHEMBL29047709 | 0.89 | TAS2R14 (0.47) | TAS2R14MAPTPOLBKDM4ERAB9A | |
| SCHEMBL30546984 | 0.88 | MAPT (0.50) | MAPTPOLBLMNAALDH1A1NPSR1 | |
| SCHEMBL29047662 | 0.88 | MAPT (0.50) | MAPTPOLBLMNAALDH1A1NPSR1 | |
| SCHEMBL29047655 | 0.87 | MAPK14 (0.48) | MAPTKDM4ELMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |