Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRACR2A | Q9BSW2 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546928 | 1.00 | TAS2R14 (0.47) | TAS2R14MAPK3MAPK1LMNAESR1 | |
| SCHEMBL30546942 | 0.93 | MAPK1 (0.42) | TAS2R14MAPK3MAPK1LMNAMAPK14 | |
| SCHEMBL29047661 | 0.93 | MAPK1 (0.42) | TAS2R14MAPK3MAPK1LMNAMAPK14 | |
| SCHEMBL29047677 | 0.90 | LMNA (0.47) | MAPK3MAPK1LMNAHTTPOLB | |
| SCHEMBL30546930 | 0.90 | LMNA (0.47) | MAPK3MAPK1LMNAHTTPOLB | |
| SCHEMBL29047640 | 0.89 | TAS2R14 (0.47) | TAS2R14LMNAMAPK14HTTPOLB | |
| SCHEMBL30546938 | 0.89 | TAS2R14 (0.47) | TAS2R14LMNAMAPK14HTTPOLB | |
| SCHEMBL29047582 | 0.87 | RXFP1 (0.48) | MAPK14SMN1; SMN2KMT2ACRACR2AALDH1A1 | |
| SCHEMBL30546978 | 0.87 | RXFP1 (0.48) | MAPK14SMN1; SMN2KMT2ACRACR2AALDH1A1 | |
| SCHEMBL29047686 | 0.87 | LMNA (0.49) | TAS2R14LMNAMAPK14KMT2ACRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |