Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23778489 | 0.81 | OPRM1 (0.41) | CYP17A1CYP19A1OPRM1OPRL1LMNA | |
| SCHEMBL9425158 | 0.73 | RAB9A (0.41) | CYP17A1CYP19A1ALDH1A1RAB9AGPR119 | |
| SCHEMBL23778868 | 0.72 | OPRM1 (0.51) | OPRM1OPRL1MEN1KMT2ALMNA | |
| SCHEMBL13650562 | 0.70 | OPRM1 (0.39) | CYP17A1CYP19A1OPRM1OPRL1SLC6A2 | |
| SCHEMBL23778929 | 0.69 | RAB9A (0.48) | CYP17A1CYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL20904051 | 0.67 | OPRM1 (0.59) | OPRM1OPRL1 | |
| SCHEMBL5890773 | 0.66 | RIPK1 (0.63) | LMNAALDH1A1RAB9ASLC6A4NAMPT | |
| SCHEMBL12344534 | 0.65 | CCR1 (0.48) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3591849 | 0.65 | GPR119 (0.53) | MEN1KMT2ALMNAALDH1A1GPR119 | |
| SCHEMBL9571667 | 0.65 | RAB9A (0.45) | KMT2ALMNAALDH1A1RAB9AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157154-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2023-05-23 | — | — | CN | disclosed |