Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009464 | 0.90 | ALDH1A1 (0.42) | ADRB2ADRB1ADRB3CTSKALDH1A1 | |
| SCHEMBL17676794 | 0.85 | MAPT (0.36) | TSHRMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL29288367 | 0.80 | ADRB2 (0.31) | ADRB2ADRB1ADRB3 | |
| SCHEMBL2986183 | 0.78 | ACACB (0.36) | MAPTCTSKGAANPSR1 | |
| SCHEMBL10321962 | 0.78 | ACACB (0.36) | MAPTCTSKGAANPSR1 | |
| SCHEMBL2990263 | 0.78 | ACACB (0.36) | MAPTCTSKGAANPSR1 | |
| SCHEMBL5370039 | 0.78 | ACACB (0.36) | MAPTCTSKGAANPSR1 | |
| Propane SCHEMBL28113027 | 0.76 | TSHR (0.39) | TSHRMAPTALDH1A1GAA | |
| SCHEMBL15856014 | 0.75 | MAPT (0.34) | MAPTKDM4EALDH1A1GAANPSR1 | |
| SCHEMBL16809083 | 0.75 | GAA (0.33) | MAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157389-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2023-05-23 | — | — | CN | disclosed |