Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189500 | 0.90 | CES2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL29047966 | 0.80 | TSHR (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL1264780 | 0.79 | MAPT (0.35) | BLM | |
| SCHEMBL7964570 | 0.74 | PDE4A (0.35) | — | |
| SCHEMBL28741130 | 0.71 | — | — | |
| SCHEMBL28698314 | 0.71 | — | — | |
| SCHEMBL21570116 | 0.71 | — | — | |
| SCHEMBL7193917 | 0.71 | SMN1; SMN2 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL28009464 | 0.71 | ALDH1A1 (0.42) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8613063 | 0.70 | EPHX1 (0.35) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980042-B | Aryldihydro-2H-benzo [ b ] [1,4] oxazine sulfonamides and related compounds as ROR gamma agonists and for the treatment of disease | 莱斯拉公司 | 2021-10-08 | — | — | CN | disclosed |