SCHEMBL29048520

SCHEMBL29048520

CN(C)Cc1ccccc1.OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
TSHR P16473 1/20 0.57
NR1H3 Q13133 7/20 0.51
NR1H2 P55055 6/20 0.51
TAAR1 Q96RJ0 1/20 0.46
MLYCD O95822 2/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CYP2C19 P33261 1/20 0.41
MTOR P42345 1/20 0.40
AOC3 Q16853 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
RORC P51449 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Alcohol SCHEMBL28250621 0.79 TSHR (0.54) TSHRNR1H3NR1H2MLYCDCYP2C19
Chloromethane SCHEMBL28157121 0.75 TSHR (0.90) ALDH1A1TSHRTAAR1NPC1RAB9A
Methyl Alcohol SCHEMBL2647148 0.75 TSHR (0.90) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL15900 0.75 TSHR (1.00) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL27766437 0.75 TSHR (1.00) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL24735547 0.75 TSHR (1.00) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL5014268 0.75 TSHR (1.00) ALDH1A1TSHRTAAR1NPC1RAB9A
Trifluoroacetic Acid SCHEMBL27585620 0.75 ALDH1A1 (0.65) ALDH1A1TSHRTAAR1MLYCDNPC1
Bromide SCHEMBL414532 0.73 TSHR (0.94) ALDH1A1TSHRTAAR1NPC1RAB9A
SCHEMBL7911439 0.73 TSHR (0.94) ALDH1A1TSHRTAAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116399965-A Method for extracting and analyzing triazole fungicide by using switchable polarity eutectic solvent 宁夏医科大学 2023-07-07 CN disclosed