SCHEMBL29050233

SCHEMBL29050233

O=Cc1cc(C=O)c(B(O)O)o1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.35
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
ERN1 O75460 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957624 0.79 CYP2A6 (0.38) CYP2A6ALDH1A1TSHRERN1
SCHEMBL14100428 0.68 ERN1 (0.38) CYP2A6ALDH1A1TSHRERN1KDM4E
SCHEMBL1133097 0.67 ALDH1A1 (0.38) CYP2A6ALDH1A1ERN1KDM4E
SCHEMBL9960823 0.62 ALDH1A1 (0.47) ALDH1A1TSHRKDM4E
SCHEMBL9221 0.62 ALDH1A1 (0.47) ALDH1A1TSHRKDM4E
SCHEMBL1108282 0.61 KDM4E (0.40) ALDH1A1KDM4E
SCHEMBL12499910 0.58
SCHEMBL6747787 0.58 ALDH1A1 (0.53) CYP2A6ALDH1A1TSHRERN1KDM4E
SCHEMBL1489158 0.57 TDP1 (0.50) ALDH1A1TSHRERN1KDM4E
SCHEMBL752776 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115785693-B N-type organic dye of 1, 2-benzothiazine, preparation method and application 南京邮电大学 2023-08-15 CN claimed
CN-115785693-A N-type organic dye of 1, 2-benzophenothiazine, preparation method and application 南京邮电大学 2023-03-14 CN claimed
CN-115785693-B N-type organic dye of 1, 2-benzothiazine, preparation method and application 南京邮电大学 2023-08-15 CN disclosed