Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 4/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22612036 | 0.71 | — | — | |
| SCHEMBL7663306 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MEN1LMNATHRBBLM | |
| SCHEMBL19138056 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNATHRBBLM | |
| SCHEMBL8051718 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MEN1LMNATHRBBLM | |
| SCHEMBL5234823 | 0.70 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1LMNATHRB | |
| SCHEMBL28435187 | 0.69 | ENPP2 (0.30) | — | |
| SCHEMBL51408 | 0.69 | — | — | |
| Water SCHEMBL3454746 | 0.67 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNATHRBBLM | |
| SCHEMBL686972 | 0.67 | — | — | |
| SCHEMBL1703143 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013080218-A1 | NOVEL INTERMEDIATES AND PROCESS FOR THE PREPARATION OF LAPATINIB AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2013-06-06 | — | — | WO | claimed |
| US-20030119178-A1 | DNA chip and its preparation | SATO KOZO (JP) | 2003-06-26 | — | — | US | claimed |
| US-20010011129-A1 | DNA chip and its preparation | FUJI PHOTO FILM CO., LTD.; | 2001-08-02 | — | — | US | claimed |
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-12-25 | — | — | US | disclosed |
| CN-119390732-A | Phosphorus-nitrogen synergistic flame-retardant biomass flame retardant and application thereof | 常州大学 | 2025-02-07 | — | — | CN | disclosed |
| US-20250011292-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2025-01-09 | — | — | US | disclosed |
| EP-4415704-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | Georgia State University Research Foundation, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| CN-116438153-A | Method for producing compound having fluorene skeleton, and compound having fluorene skeleton | 帝人株式会社 | 2023-07-14 | — | — | CN | disclosed |
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| WO-2023064368-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |
| EP-1470113-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
| US-6706703-B2 | BIS(5-ARYL-2-PYRIDYL) COMPOUND HAVING EXCELLENT IMMUNOGLOBULIN (IGE) ANTIBODY PRODUCTION INHIBITING ACTIVITY, USEFUL FOR THE PREVENTION OR TREATMENT OF ALLERGIC IMMUNE DISEASES | KOWA CO., LTD. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2003062211-A1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2003-07-31 | — | — | WO | disclosed |
| US-20030119178-A1 | DNA chip and its preparation | SATO KOZO (JP) | 2003-06-26 | — | — | US | disclosed |
| US-20030027814-A1 | Bis(5-aryl-2-pyridyl) derivatives | KOWA CO., LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
| US-20010011129-A1 | DNA chip and its preparation | FUJI PHOTO FILM CO., LTD.; | 2001-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | ALDH1A1 1622/4885KDM4E 987/4885MEN1 443/4885 |
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | ALDH1A1 1099/4885KDM4E 2554/4885MEN1 421/4885 |
| US-20030027814-A1 | Bis(5-aryl-2-pyridyl) derivatives | AHR, PAH, H1-0 | ALDH1A1 868/4885KDM4E 1363/4885MEN1 1195/4885 |
| US-20010011129-A1 | DNA chip and its preparation | STUB1, DNMT3A, PCNA | ALDH1A1 3545/4885KDM4E 769/4885MEN1 3081/4885 |
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | TET1, TET3, TRRAP | ALDH1A1 3798/4885KDM4E 150/4885MEN1 3139/4885 |
| US-20250011292-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | ACE2, RARG, ALAD | ALDH1A1 955/4885KDM4E 4281/4885MEN1 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.