SCHEMBL29957624

SCHEMBL29957624

O=Cc1cc(Br)c(B(O)O)o1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.38
ERN1 O75460 3/20 0.34
PRKDC P78527 1/20 0.33
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29050233 0.79 CYP2A6 (0.35) CYP2A6ERN1ALDH1A1TSHR
SCHEMBL3990051 0.72
SCHEMBL6169523 0.68
SCHEMBL14270899 0.68
SCHEMBL2237276 0.62 PRKDC (0.58) CYP2A6ERN1PRKDCLMNAALDH1A1
SCHEMBL31035318 0.61 KDM4E (0.48) ERN1PRKDCLMNATSHR
SCHEMBL1162124 0.60 PRKDC (0.56) CYP2A6ERN1PRKDCLMNAALDH1A1
SCHEMBL19561431 0.60 PRKDC (0.46) CYP2A6ERN1PRKDCLMNAALDH1A1
SCHEMBL9960823 0.60 ALDH1A1 (0.47) LMNAALDH1A1TSHR
SCHEMBL9221 0.60 ALDH1A1 (0.47) LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed