Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231657 | 1.00 | ALOX5AP (0.45) | ALOX5APMAP4K4MAPK14LTA4HPKM | |
| SCHEMBL21051562 | 0.75 | PDE10A (0.53) | PKMPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21232987 | 0.73 | L3MBTL1 (0.51) | MAPK14LTA4HPKMATP4AATP4B | |
| SCHEMBL30453947 | 0.73 | MAP4K4 (0.68) | ALOX5APMAP4K4MAPK14LTA4HFEN1 | |
| SCHEMBL487917 | 0.73 | MAP4K4 (0.68) | ALOX5APMAP4K4MAPK14LTA4HFEN1 | |
| SCHEMBL1758500 | 0.72 | MAPK14 (0.44) | MAP4K4MAPK14LTA4HPKMHTR2A | |
| SCHEMBL30230864 | 0.71 | NOS3 (0.42) | MAP4K4LTA4HPIK3CDMAPTCYP11B2 | |
| SCHEMBL30230970 | 0.70 | PIK3CD (0.49) | MAP4K4LTA4HPIK3CDMAPK1 | |
| SCHEMBL22952627 | 0.70 | MAPK14 (0.44) | ALOX5APMAPK14LTA4HPKMMTOR | |
| SCHEMBL6175616 | 0.69 | HTR2A (0.56) | ALOX5APFEN1HTR2AHTR2CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |