Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051805 | 0.83 | NR1H2 (0.37) | GRIN2BGRIN1DRD2SMYD2 | |
| SCHEMBL30468501 | 0.76 | PNMT (0.43) | GRIN2BGRIN1DRD2AKR1C3HPGD | |
| SCHEMBL30468430 | 0.71 | GRIN1 (0.39) | GRIN2BGRIN1DRD2SMYD2MEN1 | |
| SCHEMBL28693868 | 0.70 | MEN1 (0.37) | MEN1KMT2AHPGDABL1 | |
| SCHEMBL29052165 | 0.69 | DRD2 (0.46) | DRD2AKR1C3ADRA2APNMT | |
| SCHEMBL6622197 | 0.69 | PPARD (0.46) | MEN1KMT2A | |
| SCHEMBL30878905 | 0.69 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL5574184 | 0.68 | IDO1 (0.50) | AKR1C3MEN1KMT2A | |
| SCHEMBL1950525 | 0.68 | PNMT (0.54) | GRIN2BMEN1KMT2AHPGDADRA2A | |
| SCHEMBL22559463 | 0.68 | HTR6 (0.43) | MEN1KMT2AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |