Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 7/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.52 |
| ▸ | ULK1 | O75385 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 3/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051777 | 0.91 | BRD4 (0.54) | NTRK1JAK3NTRK3NTRK2JAK2 | |
| SCHEMBL29051926 | 0.86 | BTK (0.47) | PTK2NTRK1JAK3 | |
| SCHEMBL29051738 | 0.83 | PTK2 (0.50) | PTK2 | |
| SCHEMBL29052266 | 0.82 | INSR (0.46) | PTK2NTRK1PTK2B | |
| SCHEMBL6209873 | 0.79 | PTK2 (0.79) | PTK2NTRK1ULK1PTK2BCDK1 | |
| SCHEMBL29051826 | 0.77 | CHEK1 (0.45) | NTRK1 | |
| SCHEMBL12998622 | 0.77 | PTK2 (0.71) | PTK2ULK1PTK2BCDK1CCNB1 | |
| SCHEMBL6213126 | 0.75 | PTK2 (0.70) | PTK2NTRK1ULK1PTK2BCDK1 | |
| SCHEMBL15560708 | 0.74 | JAK3 (0.59) | PTK2NTRK1JAK3JAK2 | |
| SCHEMBL12998603 | 0.74 | PTK2 (0.75) | PTK2ULK1PTK2BCDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |