Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052928 | 0.80 | JAK2 (0.40) | GRM5RAF1BRAFMAPK1 | |
| SCHEMBL30487058 | 0.70 | PTGER4 (0.34) | HPGDKMT2AALDH1A1PDE9ASMN1; SMN2 | |
| SCHEMBL25435624 | 0.69 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTLMNACYP2C9 | |
| SCHEMBL29262338 | 0.69 | MAPT (0.47) | TSHRHPGDKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29668755 | 0.67 | DRD4 (0.36) | KMT2AALDH1A1PARP14PDE9ASMN1; SMN2 | |
| SCHEMBL30176731 | 0.67 | DRD4 (0.36) | KMT2AALDH1A1PARP14PDE9ASMN1; SMN2 | |
| SCHEMBL29924789 | 0.66 | HTT (0.36) | HPGDKMT2AALDH1A1PDE9ASMN1; SMN2 | |
| SCHEMBL30487057 | 0.66 | HTT (0.36) | HPGDKMT2AALDH1A1PDE9ASMN1; SMN2 | |
| SCHEMBL27149487 | 0.65 | CSNK2A2 (0.38) | TSHRHPGDKMT2AALDH1A1GRM5 | |
| SCHEMBL25434643 | 0.63 | NPSR1 (0.60) | ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547278-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-08-04 | — | — | CN | disclosed |