Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924789 | 0.86 | HTT (0.36) | HTTALDH1A1KMT2AMAPTPDE9A | |
| SCHEMBL30487057 | 0.86 | HTT (0.36) | HTTALDH1A1KMT2AMAPTPDE9A | |
| SCHEMBL25435624 | 0.79 | ALDH1A1 (0.51) | HTTALDH1A1MAPTLMNAPKM | |
| SCHEMBL9320290 | 0.78 | GABRP (0.40) | PTGER4HTTALDH1A1MAPTLMNA | |
| SCHEMBL29262338 | 0.77 | MAPT (0.47) | HTTALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL30149296 | 0.71 | GLP1R (0.41) | PTGER4HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL25543735 | 0.71 | GLP1R (0.41) | PTGER4HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL29052841 | 0.70 | TSHR (0.38) | HTTALDH1A1KMT2APDE9ALMNA | |
| SCHEMBL6301028 | 0.70 | MAPK1 (0.41) | PTGER4HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL29668755 | 0.70 | DRD4 (0.36) | HTTALDH1A1KMT2APDE9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974037-A | Benzobicyclo compound and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-11-15 | — | — | CN | disclosed |