Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924789 | 1.00 | HTT (0.36) | HTTPDE9ALGALS8ALDH1A1HCAR3 | |
| SCHEMBL30487058 | 0.86 | PTGER4 (0.34) | HTTPDE9AALDH1A1NPSR1PARP1 | |
| SCHEMBL29241233 | 0.76 | NPSR1 (0.60) | LGALS8ALDH1A1NPSR1HTR2BSMN1; SMN2 | |
| SCHEMBL25434643 | 0.76 | NPSR1 (0.60) | LGALS8ALDH1A1NPSR1HTR2BSMN1; SMN2 | |
| SCHEMBL29491599 | 0.73 | NPSR1 (0.47) | LGALS8ALDH1A1HCAR3NPSR1HTR2B | |
| SCHEMBL29668755 | 0.73 | DRD4 (0.36) | HTTPDE9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30176731 | 0.73 | DRD4 (0.36) | HTTPDE9AALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28057569 | 0.71 | NPSR1 (0.56) | LGALS8ALDH1A1HCAR3NPSR1KDM4E | |
| SCHEMBL25435624 | 0.70 | ALDH1A1 (0.51) | HTTLGALS8ALDH1A1NPSR1KDM4E | |
| SCHEMBL25435836 | 0.67 | GLP1R (0.49) | HTTALDH1A1GLP1RHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974037-A | Benzobicyclo compound and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-11-15 | — | — | CN | disclosed |