Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 19/20 | 0.81 |
| ▸ | SIRT1 | Q96EB6 | 14/20 | 0.81 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.71 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055302 | 1.00 | SIRT2 (0.81) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL19253993 | 0.92 | SIRT2 (0.75) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL2963543 | 0.89 | SIRT2 (0.76) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL7689520 | 0.89 | SIRT2 (0.76) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL21357647 | 0.89 | SIRT2 (0.76) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL4787188 | 0.89 | SIRT2 (0.76) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL25887999 | 0.88 | SIRT2 (0.67) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL6199045 | 0.88 | SIRT2 (0.65) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL17279329 | 0.88 | SIRT2 (0.74) | SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL11308449 | 0.88 | SIRT2 (0.74) | SIRT2SIRT1SIRT3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178340-B | PROTAC compound, preparation method and pharmaceutical composition | 细胞生态海河实验室 | 2023-08-18 | — | — | CN | claimed |