Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.76 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.76 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.65 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787188 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL21357647 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL7689520 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL17279329 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL11308449 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL17694104 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL150166 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL11332452 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL4126228 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| Hydrochloric Acid SCHEMBL4438043 | 0.93 | CTSL (0.70) | SIRT2SIRT1CTSLCTSSSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371328-A | Preparation method of 8-amino octanoic acid | 苏州昊帆生物股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119371328-A | Preparation method of 8-amino octanoic acid | 苏州昊帆生物股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| US-20210085798-A1 | IMMUNITY LINKER MOLECULES AND THEIR USE IN THE TREATMENT OF INFECTIOUS DISEASES | CENTAURI THERAPEUTICS LIMITED (GB) | 2021-03-25 | — | — | US | disclosed |
| EP-3765155-A1 | IMMUNITY LINKER MOLECULES AND THEIR USE IN THE TREATMENT OF INFECTIOUS DISEASES | Centauri Therapeutics Limited (GB) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019175590-A1 | IMMUNITY LINKER MOLECULES AND THEIR USE IN THE TREATMENT OF INFECTIOUS DISEASES | CENTAURI THERAPEUTICS LIMITED (GB) | 2019-09-19 | — | — | WO | disclosed |
| US-7767811-B2 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20060293536-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2006-12-28 | — | — | US | disclosed |
| US-7057038-B2 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1419125-A4 | KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | UNIV BRANDEIS (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20050020849-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | DENG LI (US) | 2005-01-27 | — | — | US | disclosed |
| EP-1305270-B1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | UNIV BRANDEIS (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030166963-A1 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-04 | — | — | US | disclosed |
| US-6562967-B2 | Drug screening; purity | BRANDEIS UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| EP-1305270-A1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | Brandeis University (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003011799-A1 | KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | BRANDEIS UNIVERSITY (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20020165393-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |
| US-20020151744-A1 | Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-17 | — | — | US | disclosed |
| WO-2002010096-A1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | BRANDEIS UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
| EP-0932619-A1 | MACROCYCLIC PEPTIDES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | Ortho-McNeil Pharmaceutical, Inc. (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1997030080-A1 | MACROCYCLIC PEPTIDES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165393-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | SIRT2 4038/4885SIRT1 4474/4885CTSL 3226/4885 |
| US-20050020849-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | SIRT2 4154/4885SIRT1 4495/4885CTSL 3302/4885 |
| US-20060293536-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | SIRT2 4154/4885SIRT1 4495/4885CTSL 3302/4885 |
| US-20030166963-A1 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids | ADH5, ADH1C, TST | SIRT2 4058/4885SIRT1 4509/4885CTSL 3348/4885 |
| US-20020151744-A1 | Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids | ADH5, ADH1C, TST | SIRT2 4236/4885SIRT1 4659/4885CTSL 3429/4885 |
| US-20210085798-A1 | IMMUNITY LINKER MOLECULES AND THEIR USE IN THE TREATMENT OF INFECTIOUS DISEASES | MYD88, MAVS, TLR3 | SIRT2 1140/4885SIRT1 1085/4885CTSL 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.