Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.76 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.76 |
| ▸ | CTSL | P07711 | 1/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.65 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963543 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL4787188 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL21357647 | 1.00 | SIRT2 (0.76) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL17279329 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL11308449 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL17694104 | 0.99 | SIRT2 (0.74) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL150166 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL11332452 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| SCHEMBL4126228 | 0.95 | CTSL (0.72) | SIRT2SIRT1CTSLCTSSSIRT3 | |
| Hydrochloric Acid SCHEMBL4438043 | 0.93 | CTSL (0.70) | SIRT2SIRT1CTSLCTSSSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017684-B1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1017684-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6083479-A | Contrast media for infarction and necrosis imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| WO-1999016757-A1 | CONTRASTING AGENT FOR INFARCT AND NECROSIS IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |