Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHAT | P28329 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532692 | 0.80 | TTR (0.37) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL27693757 | 0.78 | MAOB (0.37) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL7324466 | 0.77 | TRPA1 (0.37) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL30781477 | 0.76 | CHAT (0.39) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL4595773 | 0.76 | CHAT (0.39) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL27570573 | 0.75 | HDAC1 (0.37) | TTRALOX5PTGS1PTGS2CMA1 | |
| SCHEMBL4438933 | 0.74 | MAOB (0.39) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL7941862 | 0.74 | CHAT (0.37) | TTRALOX5PTGS1PTGS2CHAT | |
| SCHEMBL9639696 | 0.73 | ALDH1A1 (0.38) | CMA1HDAC1EGFRMMP1MMP2 | |
| SCHEMBL6837817 | 0.73 | CHAT (0.35) | TTRALOX5PTGS1PTGS2CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101123995-B | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA | 2011-11-16 | — | — | CN | disclosed |
| EP-2216050-A1 | UTILIZATION OF NOVEL COMPOUNDS WITH AMYLOID AFFINITY AND METHOD OF PRODUCING THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2216052-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |
| CN-101123995-A | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2008-02-13 | — | — | CN | disclosed |