Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941066 | 0.98 | — | — | |
| SCHEMBL598305 | 0.98 | — | — | |
| SCHEMBL9683659 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28100195 | 0.95 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL2905354 | 0.95 | — | — | |
| Bromide SCHEMBL2905446 | 0.85 | ALDH1A1 (0.34) | — | |
| SCHEMBL6574015 | 0.84 | — | — | |
| SCHEMBL15069744 | 0.84 | — | — | |
| Bromide SCHEMBL8848890 | 0.84 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL29989378 | 0.83 | GNAI3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235752-B1 | PROCESS FOR RECOVERING ORGANIC HYDROXIDES FROM WASTE SOLUTIONS | SACHEM INC (US) | 2010-07-28 | — | — | EP | disclosed |
| EP-1235752-A4 | PROCESS FOR RECOVERING ORGANIC HYDROXIDES FROM WASTE SOLUTIONS | SACHEM INC (US) | 2006-02-22 | — | — | EP | disclosed |
| EP-1235752-A1 | PROCESS FOR RECOVERING ORGANIC HYDROXIDES FROM WASTE SOLUTIONS | Sachem, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001010785-A1 | PROCESS FOR RECOVERING ORGANIC HYDROXIDES FROM WASTE SOLUTIONS | SACHEM, INC. (US) | 2001-02-15 | — | — | WO | disclosed |