Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058927 | 0.87 | EPAS1 (1.00) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL29058951 | 0.80 | GPBAR1 (0.78) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL12204335 | 0.79 | LMNA (0.79) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL29058683 | 0.76 | ALDH1A1 (0.82) | LMNAGPBAR1USP2MEN1KMT2A | |
| SCHEMBL30395450 | 0.75 | EPAS1 (1.00) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL20507144 | 0.75 | CYP2C19 (0.73) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL13654932 | 0.75 | GPBAR1 (0.69) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL30395319 | 0.75 | GPBAR1 (0.69) | EPAS1LMNAGPBAR1USP2MEN1 | |
| SCHEMBL5533828 | 0.74 | LMNA (0.74) | LMNAGPBAR1USP2MEN1KMT2A | |
| SCHEMBL31546967 | 0.73 | MAPT (0.76) | EPAS1LMNAGPBAR1USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116236478-A | Application of aromatic heterocyclic formamide compound | 浙江大学 | 2023-06-09 | — | — | CN | disclosed |