Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | CPT2 | P23786 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25353036 | 0.91 | FFAR1 (0.64) | FFAR1CPT2TDP1ALDH1A1SLC13A5 | |
| SCHEMBL10627086 | 0.86 | FFAR1 (0.63) | FFAR1CPT2TDP1MAPTRXFP1 | |
| SCHEMBL26060195 | 0.84 | FFAR1 (0.56) | FFAR1CPT2TDP1ALDH1A1SLC13A5 | |
| SCHEMBL28797333 | 0.80 | FFAR1 (0.55) | FFAR1CPT2TDP1ALDH1A1SLC13A5 | |
| SCHEMBL13882162 | 0.79 | LTB4R (0.40) | ALDH1A1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL25996677 | 0.78 | FFAR1 (0.56) | FFAR1CPT2TDP1MAPTRXFP1 | |
| SCHEMBL25995659 | 0.77 | FFAR1 (0.47) | FFAR1CPT2TDP1ALDH1A1SLC13A5 | |
| SCHEMBL8037883 | 0.76 | FFAR1 (1.00) | FFAR1CPT2TDP1ALDH1A1 | |
| SCHEMBL5523390 | 0.76 | FFAR1 (1.00) | FFAR1CPT2TDP1ALDH1A1 | |
| SCHEMBL1834211 | 0.76 | FFAR1 (1.00) | FFAR1CPT2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309053-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-8268291-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120100073-A1 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE | WASHINGTON UNIVERSITY (US) | 2012-04-26 | — | — | US | disclosed |
| CN-102421454-A | Pet radiotracers for imaging fatty acid metablolism and storage | UNIV WASHINGTON | 2012-04-18 | — | — | CN | disclosed |
| EP-2427218-A2 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABLOLISM AND STORAGE | Washington University (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129572-A2 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABLOLISM AND STORAGE | WASHINGTON UNIVERSITY (US) | 2010-11-11 | — | — | WO | disclosed |
| US-7790142-B2 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | THE GENERAL HOSPITAL CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090156848-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2009-06-18 | — | — | US | disclosed |
| US-20080214853-A1 | Labeled cycloalkylidene-containing fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart or tumor | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080214851-A1 | Synthesis of labeled fatty acid analogs for use in tomography | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080213178-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080213173-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor; endo-vinylic variants of cycloalkyl-substituted heptadecanoic acid for example | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080206135-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | THE GENERAL HOSPITAL CORPORATION (US) | 2008-08-28 | — | — | US | disclosed |
| EP-1622602-B1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | GEN HOSPITAL CORP (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20080095702-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor | THE GENERAL HOSPITAL CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| EP-1622602-A4 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | GEN HOSPITAL CORP (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1622602-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004093650-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |
| US-4764358-A | Radiolabeled dimethyl branched long chain fatty acid for heart imaging | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1988-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214851-A1 | Synthesis of labeled fatty acid analogs for use in tomography | FFAR4, FFAR3, FFAR2 | FFAR1 5/4885CPT2 54/4885TDP1 4549/4885 |
| US-20080214853-A1 | Labeled cycloalkylidene-containing fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart or tumor | FABP3, FFAR2, FFAR1 | FFAR1 3/4885CPT2 23/4885TDP1 4610/4885 |
| US-20080206135-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | FFAR3, FFAR2, FFAR1 | FFAR1 3/4885CPT2 79/4885TDP1 3855/4885 |
| US-20080213173-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor; endo-vinylic variants of cycloalkyl-substituted heptadecanoic acid for example | FABP3, FABP1, FFAR2 | FFAR1 4/4885CPT2 61/4885TDP1 4593/4885 |
| US-20080095702-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor | FABP3, FABP1, FFAR2 | FFAR1 4/4885CPT2 31/4885TDP1 4778/4885 |
| US-20080213178-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | FFAR3, FFAR2, FFAR1 | FFAR1 3/4885CPT2 79/4885TDP1 3855/4885 |
| US-20120100073-A1 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE | LIPC, PNLIP, FFAR1 | FFAR1 3/4885CPT2 93/4885TDP1 1601/4885 |
| US-20090156848-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | FABP3, FABP1, SLC27A2 | FFAR1 10/4885CPT2 92/4885TDP1 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.