Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059430 | 0.89 | MEN1 (0.42) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL29059448 | 0.80 | GGT1 (0.43) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL27849653 | 0.79 | POLB (0.53) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL29059366 | 0.78 | SIGMAR1 (0.44) | KMT2ASIGMAR1GAACYP2C19CYP2D6 | |
| SCHEMBL7469306 | 0.77 | GGT1 (0.54) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL27699637 | 0.77 | MME (0.56) | GGT1KMT2ASIGMAR1 | |
| SCHEMBL27699635 | 0.77 | MME (0.56) | GGT1KMT2ASIGMAR1 | |
| SCHEMBL8609013 | 0.77 | GGT1 (0.54) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL7469320 | 0.77 | GGT1 (0.54) | GGT1KMT2AMEN1TSHRSIGMAR1 | |
| SCHEMBL19419061 | 0.75 | GGT1 (0.52) | GGT1KMT2AMEN1TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601158-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-15 | — | — | CN | disclosed |