Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244045 | 0.80 | KMT2A (0.35) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL18167877 | 0.75 | STK17B (0.37) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL22509297 | 0.74 | PAX8 (0.39) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL22502038 | 0.72 | STK17B (0.35) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL27880856 | 0.69 | GRM5 (0.36) | KMT2A | |
| SCHEMBL24323341 | 0.69 | STK17B (0.38) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL8819965 | 0.68 | SYK (0.35) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL4439238 | 0.68 | SMN1; SMN2 (0.36) | LMNAKMT2ASTK17BSTK17AHSP90AA1 | |
| SCHEMBL20822309 | 0.68 | ELANE (0.32) | — | |
| SCHEMBL24299010 | 0.68 | LMNA (0.34) | LMNAKMT2ASTK17BSTK17AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783204-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116670143-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-29 | — | — | CN | disclosed |