SCHEMBL29060652

SCHEMBL29060652

NC(=O)c1ccc(C2(NC(=O)c3ccccc3)CCCCC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ADRB2 P07550 1/20 0.45
SSTR4 P31391 1/20 0.45
HDAC1 Q13547 3/20 0.43
HDAC3 O15379 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
CTSK P43235 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27880342 0.83 SSTR4 (0.40) LMNAPOLBL3MBTL1CYP3A4PARP1
SCHEMBL10605790 0.83 LMNA (0.51) LMNAL3MBTL1MAPTCYP2C19BLM
SCHEMBL28793250 0.80 CXCR3 (0.51) LMNAPOLBL3MBTL1MAPTCYP2C19
SCHEMBL16249346 0.79 WDR91 (0.53) POLBL3MBTL1HDAC1HDAC3HDAC2
SCHEMBL8781647 0.77 PDE2A (0.44) LMNAL3MBTL1MAPTBLMADRB2
SCHEMBL28849376 0.77 SSTR4 (0.56) SSTR4HDAC1HDAC3HDAC2HDAC6
SCHEMBL9640292 0.75 SSTR4 (0.54) POLBSSTR4HDAC1HDAC3HDAC2
SCHEMBL27864029 0.75 PARP10 (0.39) POLBL3MBTL1CYP3A4PARP1MAPT
SCHEMBL11728170 0.75 ADRB2 (0.54) LMNAL3MBTL1MAPTCYP2C19BLM
SCHEMBL9698835 0.75 ADRB2 (0.54) LMNAPOLBL3MBTL1MAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113316607-B Fiber sheet and method for producing same 花王株式会社 2023-07-28 CN claimed
CN-113316607-B Fiber sheet and method for producing same 花王株式会社 2023-07-28 CN disclosed