Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10605790 | 0.89 | LMNA (0.51) | CXCR3AKT1L3MBTL1PDE2AHDAC3 | |
| SCHEMBL20898400 | 0.85 | WDR91 (0.54) | WDR91CXCR3POLBL3MBTL1HDAC3 | |
| SCHEMBL28545624 | 0.82 | NPC1 (0.50) | WDR91CXCR3PTGS2POLBCCR1 | |
| SCHEMBL16161986 | 0.82 | HDAC4 (0.47) | WDR91CXCR3SLC6A9HDAC3HDAC1 | |
| SCHEMBL28793250 | 0.82 | CXCR3 (0.51) | CXCR3POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL20898603 | 0.81 | IDO1 (0.59) | — | |
| SCHEMBL14879488 | 0.81 | WDR91 (0.50) | WDR91CXCR3PTGS2POLBCCR1 | |
| SCHEMBL20899151 | 0.81 | FLT1 (0.52) | WDR91CXCR3POLBFLT1FLT4 | |
| SCHEMBL29060652 | 0.79 | LMNA (0.47) | POLBL3MBTL1PDE2AHDAC3HDAC1 | |
| SCHEMBL22438959 | 0.79 | WDR91 (0.57) | WDR91CXCR3L3MBTL1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS, INCORPORATED | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343019-A1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | ARG1, ARG2, PRMT1 | WDR91 975/4885CXCR3 1039/4885PTGS2 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.