Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062130 | 1.00 | GRIA1 (0.49) | GRIA1GRIA3CYP1A2GRIA2GRIA4 | |
| SCHEMBL4813618 | 0.77 | THRB (0.47) | GRIA1GRIA3CYP1A2GRIA2GRIA4 | |
| SCHEMBL14945011 | 0.73 | GRIA1 (0.49) | GRIA1GRIA3GRIA2GRIA4PKM | |
| SCHEMBL1913013 | 0.72 | TRPM8 (0.45) | CYP1A2ALDH1A1MAPTRECQL | |
| SCHEMBL8249166 | 0.72 | ACE2 (0.42) | ALDH1A1 | |
| SCHEMBL691738 | 0.72 | HTT (0.44) | ALOX15HSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL24387889 | 0.71 | SCN5A (0.40) | CYP3A4NFKB1THPOALDH1A1MAPT | |
| SCHEMBL15469204 | 0.71 | CYP1A2 (0.37) | GRIA1GRIA3CYP1A2GRIA2GRIA4 | |
| SCHEMBL26965365 | 0.71 | PSMB8 (0.43) | CYP1A2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27133930 | 0.71 | PSMB8 (0.43) | CYP1A2MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262734-B | Oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-116262734-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |