Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021111 | 1.00 | CTSK (0.39) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL23976292 | 0.87 | CTSK (0.43) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL27250384 | 0.86 | ITGB3 (0.41) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL16119268 | 0.86 | ITGB3 (0.41) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL28762293 | 0.86 | ITGB3 (0.41) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL19606036 | 0.85 | ITGB3 (0.45) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL15945081 | 0.85 | CTSK (0.50) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL1127859 | 0.83 | CTSK (0.43) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL5828772 | 0.83 | CTSK (0.48) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL12676608 | 0.82 | CTSK (0.42) | CTSKCTSSCTSLCTSBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |