Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23976292 | 0.92 | CTSK (0.43) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL14366085 | 0.86 | ITGB3 (0.50) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL6646260 | 0.86 | ITGB3 (0.50) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL27546587 | 0.85 | ITGB3 (0.49) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL1904291 | 0.85 | ITGB3 (0.54) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL27546586 | 0.85 | ITGB3 (0.49) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL31341192 | 0.85 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL2324580 | 0.85 | ITGB3 (0.54) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL8823986 | 0.85 | ITGB3 (0.54) | CTSKCTSSITGB3ITGA2BCYP1A2 | |
| SCHEMBL3732677 | 0.84 | CTSK (0.50) | CTSKCTSSITGB3ITGA2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148371-B2 | Method for producing lysine derivative | AJINOMOTO CO., INC. (JP) | 2006-12-12 | — | — | US | disclosed |
| US-7012152-B2 | Method for producing lysine derivative | AJINOMOTO CO., INC. (JP) | 2006-03-14 | — | — | US | disclosed |
| US-20060004103-A1 | Method for producing lysine derivative | AJINOMOTO CO., INC. (JP) | 2006-01-05 | — | — | US | disclosed |
| US-20040054216-A1 | Method for producing lysine derivative | AJINOMOTO CO., INC. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6664412-B2 | Protecting amino group or amino group and carboxyl group of optically active 2-amino-6-methyl-6-nitroheptanoic acid with protecting group, reducing nitro group to synthesize 6,6-dimethyllysine and reacting this with acetic acid | AJINOMOTO CO., INC. (JP) | 2003-12-16 | — | — | US | disclosed |
| US-20030105351-A1 | Method for producing lysine derivative | AJINOMOTO CO. INC (JP) | 2003-06-05 | — | — | US | disclosed |
| US-20020042537-A1 | Method for producing lysine derivative | AJINOMOTO CO., INC. (JP) | 2002-04-11 | — | — | US | disclosed |
| EP-1179599-A2 | Method for producing lysine derivative | Ajinomoto Co., Inc. (JP) | 2002-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105351-A1 | Method for producing lysine derivative | JMJD6, SIRT6, KDM6A | CTSK 1307/4885CTSS 2101/4885ITGB3 4046/4885 |
| US-20040054216-A1 | Method for producing lysine derivative | JMJD6, SIRT6, KDM6A | CTSK 1307/4885CTSS 2101/4885ITGB3 4046/4885 |
| US-20020042537-A1 | Method for producing lysine derivative | JMJD6, SIRT6, KDM6A | CTSK 1307/4885CTSS 2101/4885ITGB3 4046/4885 |
| US-20060004103-A1 | Method for producing lysine derivative | JMJD6, SIRT6, KDM6A | CTSK 1307/4885CTSS 2101/4885ITGB3 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.