Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265196 | 0.81 | LMNA (0.41) | LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2966870 | 0.81 | — | — | |
| SCHEMBL5968099 | 0.81 | SCN9A (0.36) | SCN9ANAAAASAH1KDM5AKDM4C | |
| SCHEMBL25846419 | 0.81 | SCN9A (0.36) | SCN9ANAAAASAH1KDM5AKDM4C | |
| SCHEMBL30937187 | 0.81 | LMNA (0.33) | SCN9ALMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3677140 | 0.77 | LMNA (0.52) | LMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2590590 | 0.77 | — | — | |
| SCHEMBL24112751 | 0.77 | PSEN1 (0.44) | SCN9ANAAAASAH1KDM5AKDM4C | |
| SCHEMBL11751290 | 0.75 | LMNA (0.55) | NAAALMNASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2937173 | 0.75 | LMNA (0.55) | NAAALMNASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |