SCHEMBL2937173

SCHEMBL2937173

O=C(Cl)OCC1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC1A1 P43005 3/20 0.42
PARP15 Q460N3 2/20 0.40
PARP10 Q53GL7 2/20 0.40
THRA P10827 2/20 0.39
THRB P10828 2/20 0.39
TP53 P04637 1/20 0.39
EPHX1 P07099 3/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX5 P09917 1/20 0.36
NAAA Q02083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11751290 1.00 LMNA (0.55) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL3677140 0.98 LMNA (0.52) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL2590590 0.93
SCHEMBL2966870 0.88
SCHEMBL2265196 0.88 LMNA (0.41) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL1669840 0.81 LMNA (0.59) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL23129641 0.79 LMNA (0.57) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL1864716 0.79 LMNA (0.62) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL4631096 0.79 LMNA (0.62) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL8393247 0.79 LMNA (0.57) LMNASLC1A3SLC1A2SLC1A1PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059951-A Process for preparing peroxyesters or peroxycarbonates 诺力昂化学品国际有限公司 2024-12-03 CN claimed
CN-108276386-B Cyclohexyl methoxy formyl amino quinazoline compound and preparation and application thereof 浙江工业大学 2020-10-09 CN claimed
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof ENANTA PHARM INC (US) 2025-12-11 US disclosed
WO-2025224262-A1 COMBINATION THERAPIES COMPRISING A CDK2 DEGRADER AND A CDK4/6 INHIBITOR MONTE ROSA THERAPEUTICS AG (CH) 2025-10-30 WO disclosed
EP-4608816-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF Monte Rosa Therapeutics AG (CH) 2025-09-03 EP disclosed
US-20250263395-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2025-08-21 US disclosed
US-12384753-B2 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2025-08-12 US disclosed
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2025-06-26 US disclosed
EP-4499612-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2025-02-05 EP disclosed
CN-119059951-A Process for preparing peroxyesters or peroxycarbonates 诺力昂化学品国际有限公司 2024-12-03 CN disclosed
CN-118974020-A Substituted 3-aminoindazole derivatives as kinase inhibitors 内尔维亚诺医疗科学公司 2024-11-15 CN disclosed
US-5559232-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-09-24 US disclosed
US-5444068-A Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-22 US disclosed
US-5426190-A Preparation of N-(organocarbonyloxy)-succinimide derivatives of N-hydroxysuccinimide PPG INDUSTRIES, INC. (US) 1995-06-20 US disclosed
US-4859229-A HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1989-08-22 US disclosed
US-4661145-A HYDRIDIZATION AGENTS ROHM AND HAAS COMPANY (US) 1987-04-28 US disclosed
US-4515787-A Steroids ROUSSEL UCLAF (FR) 1985-05-07 US disclosed
US-4415571-A HYPOTENSIVE AGENTS; THROMBOSIS; ANTICOAGULANTS; CARDIOVASCULAR DISORDDERS BASF AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
US-4345934-A Method of producing hybrid cereal grain seeds by application of 1-aryl-1,4-dihydro-4-oxo(thio)-pyridazines ROHM AND HAAS COMPANY (US) 1982-08-24 US disclosed
US-3939265-A MIXTURE OF AN ANABOLISANT AND ESTROGENIC STEROID GRANDADAM JEAN ANDRE 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS CDK1, CDK11A, CDK3 LMNA 1723/4885SLC1A3 3122/4885SLC1A2 3927/4885
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof HSD17B1, HSD17B13, HSD17B3 LMNA 2111/4885SLC1A3 2157/4885SLC1A2 3176/4885
US-12384753-B2 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof HSD17B1, HSD17B13, HSD17B3 LMNA 2111/4885SLC1A3 2157/4885SLC1A2 3176/4885
US-20250263395-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF CDK2, SKP2, CDK1 LMNA 2140/4885SLC1A3 4485/4885SLC1A2 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.