SCHEMBL2265196

SCHEMBL2265196

O=C(Cl)OCC1CCC(COC(=O)Cl)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
SLC1A3 P43003 4/20 0.36
SLC1A2 P43004 4/20 0.36
SLC1A1 P43005 4/20 0.36
PARP15 Q460N3 1/20 0.34
PARP10 Q53GL7 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
PTGIR P43119 8/20 0.34
PTGDR Q13258 4/20 0.34
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33
ALDH1A1 P00352 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
MAOB P27338 1/20 0.32
CHRM3 P20309 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2966870 1.00
SCHEMBL3677140 0.90 LMNA (0.52) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL2590590 0.90
SCHEMBL11751290 0.88 LMNA (0.55) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL2937173 0.88 LMNA (0.55) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL20656899 0.82 SIGMAR1 (0.42) ACHE
SCHEMBL20656958 0.81 HTR4 (0.44) BCHEACHECHRM3
SCHEMBL29063243 0.81 SCN9A (0.36) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL30937187 0.81 LMNA (0.33) LMNASLC1A3SLC1A2SLC1A1
SCHEMBL9723991 0.81 PKM (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059951-A Process for preparing peroxyesters or peroxycarbonates 诺力昂化学品国际有限公司 2024-12-03 CN claimed
CN-119059951-A Process for preparing peroxyesters or peroxycarbonates 诺力昂化学品国际有限公司 2024-12-03 CN disclosed
EP-2651917-A1 DIMERIC IAP INHIBITORS Novartis AG (CH) 2013-10-23 EP disclosed
US-20130266590-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2013-10-10 US disclosed
US-8445440-B2 Dimeric IAP inhibitors NOVARTIS AG (CH) 2013-05-21 US disclosed
EP-2539333-A1 DIMERIC IAP INHIBITORS Novartis AG (CH) 2013-01-02 EP disclosed
WO-2012080260-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2012-06-21 WO disclosed
WO-2011104266-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-09-01 WO disclosed
US-20110206690-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-08-25 US disclosed
EP-1071662-B1 PEROXIDES, THEIR PREPARATION PROCESS AND USE AKZO NOBEL NV (NL) 2004-08-04 EP disclosed
US-6770774-B2 USING A PEROXY COMPOUND AS CURING AGENT, POLYMERIZATION CATALYST AKZO NOBEL N.V. (NL) 2004-08-03 US disclosed
US-20030073861-A1 Using a peroxy compound as curing agent, polymerization catalyst VAN DE BOVENKAMP-BOUWMAN ANNA (NL) 2003-04-17 US disclosed
US-6482970-B1 Peroxides, their preparation process and use AKZO NOBEL NV (NL) 2002-11-19 US disclosed
US-5426190-A Preparation of N-(organocarbonyloxy)-succinimide derivatives of N-hydroxysuccinimide PPG INDUSTRIES, INC. (US) 1995-06-20 US disclosed
EP-0078885-B1 DI(ACYLPEROXY)-1,4-CYCLOHEXANE DIMETHANOL-BIS-CARBONATES AND METHODS OF USE U.S. Peroxygen Company (US) 1986-01-29 EP disclosed
EP-0078885-A1 Di(acylperoxy)-1,4-cyclohexane dimethanol-bis-carbonates and methods of use U.S. Peroxygen Company (US) 1983-05-18 EP disclosed
US-4372877-A ADDITION POLYMERIZATION CATALYSTS, CURING AGENTS FOR UNSATURATED POLYESTERS U.S. PEROXYGEN COMPANY (US) 1983-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130266590-A1 DIMERIC IAP INHIBITORS XIAP, BIRC5, BIRC2 LMNA 182/4885SLC1A3 4034/4885SLC1A2 4356/4885
US-20110206690-A1 DIMERIC IAP INHIBITORS XIAP, BIRC5, BIRC2 LMNA 198/4885SLC1A3 4126/4885SLC1A2 4283/4885
US-20030073861-A1 Using a peroxy compound as curing agent, polymerization catalyst PRDX4, ACOX3, PRDX2 LMNA 2260/4885SLC1A3 3909/4885SLC1A2 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.