SCHEMBL2966870

SCHEMBL2966870

O=C(Cl)OCC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2265196 1.00 LMNA (0.41)
SCHEMBL3677140 0.90 LMNA (0.52)
SCHEMBL2590590 0.90
SCHEMBL11751290 0.88 LMNA (0.55)
SCHEMBL2937173 0.88 LMNA (0.55)
SCHEMBL20656899 0.82 SIGMAR1 (0.42)
SCHEMBL20656958 0.81 HTR4 (0.44)
SCHEMBL29063243 0.81 SCN9A (0.36)
SCHEMBL30937187 0.81 LMNA (0.33)
SCHEMBL9723991 0.81 PKM (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049054-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA AS (DK) 2026-02-19 US disclosed
US-12473301-B2 Isoquinoline compounds for the treatment of cancer GENENTECH, INC. (US) 2025-11-18 US disclosed
US-12391644-B2 Potassium channel inhibitors SANIONA A/S (DK) 2025-08-19 US disclosed
EP-3941903-B1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA AS (DK) 2025-07-16 EP disclosed
US-20250206724-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2025-06-26 US disclosed
EP-3860995-B1 ISOQUINOLINE COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN LA ROCHE (CH) 2025-04-16 EP disclosed
EP-4499612-A1 SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2025-02-05 EP disclosed
EP-4486747-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2025-01-08 EP disclosed
CN-118974020-A Substituted 3-aminoindazole derivatives as kinase inhibitors 内尔维亚诺医疗科学公司 2024-11-15 CN disclosed
CN-118930552-A Isobenzofuran-1 (3H) -one compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-11-12 CN disclosed
EP-1255748-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-13 EP disclosed
WO-2001060813-A1 BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-23 WO disclosed
US-4859229-A HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1989-08-22 US disclosed
US-4440683-A Cyclization to form cephem ring and azetidinone intermediates therefor SHIONOGI & CO., LTD. (JP) 1984-04-03 US disclosed
US-4415571-A HYPOTENSIVE AGENTS; THROMBOSIS; ANTICOAGULANTS; CARDIOVASCULAR DISORDDERS BASF AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
US-4376731-A 2-NITRILES THEREOF BOEHRINGER MANNHEIM GMBH (DE) 1983-03-15 US disclosed
US-4346218-A DECYCLIZATION OF AN AZETIDINOTHIAZOLINE SHIONOGI & CO., LTD. (JP) 1982-08-24 US disclosed
US-4332722-A BICYCLIC AZETIDINOTHIAZOLINES SHIONOGI & CO., LTD. (JP) 1982-06-01 US disclosed
US-4160085-A Cyclization to form cephem ring and intermediates therefor SHIONOGI & CO., LTD. (JP) 1979-07-03 US disclosed
US-4079181-A INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS SHIONOGI & CO., LTD. (JA) 1978-03-14 US disclosed