Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 4/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096595 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL30567599 | 0.83 | COPS5 (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL29063449 | 0.78 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDPKM | |
| SCHEMBL535765 | 0.74 | L3MBTL1 (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL2082444 | 0.74 | ALDH1A1 (0.65) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3066792 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3095838 | 0.72 | FBP1 (0.66) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL11700337 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL8071199 | 0.72 | ALDH1A1 (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL794531 | 0.72 | ALDH1A1 (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693467-B | Thiazole amine MBL inhibitor and preparation method and application thereof | 四川大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-116693467-A | Thiazole amine MBL inhibitor and preparation method and application thereof | 四川大学 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160582-A1 | THIAZOLAMINE MBL INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川大学 | 2023-08-31 | — | — | WO | disclosed |