Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 19/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064687 | 0.94 | TXNRD1 (0.39) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL29878520 | 0.89 | TXNRD1 (0.43) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL16469705 | 0.89 | TXNRD1 (0.43) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL29371318 | 0.89 | TXNRD1 (0.43) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL16469819 | 0.89 | TXNRD1 (0.43) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL29064663 | 0.88 | TXNRD1 (0.42) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL29064682 | 0.87 | ALDH1A1 (0.31) | TXNRD1MAPTMAPK1 | |
| SCHEMBL29064686 | 0.87 | TXNRD1 (0.40) | TXNRD1GSRXDHS1PR4MAPT | |
| SCHEMBL29064665 | 0.87 | ALDH1A1 (0.35) | TXNRD1MAPTMAPK1 | |
| SCHEMBL29064683 | 0.87 | TXNRD1 (0.42) | TXNRD1GSRXDHS1PR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |