Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16470351 | 0.90 | MAPT (0.38) | ALDH1A1KDM4EKMT2AMAOAMAPT | |
| SCHEMBL16470379 | 0.90 | ALDH1A1 (0.33) | ALDH1A1KDM4EKMT2AMAOAMAPT | |
| SCHEMBL29064677 | 0.88 | KDM4E (0.34) | ALDH1A1KDM4EKMT2AMAOAL3MBTL1 | |
| SCHEMBL29064660 | 0.87 | TXNRD1 (0.43) | MAPTMAPK1TXNRD1 | |
| SCHEMBL29064682 | 0.85 | ALDH1A1 (0.31) | ALDH1A1MAOAMAPTMAPK1L3MBTL1 | |
| SCHEMBL29064687 | 0.82 | TXNRD1 (0.39) | MAPTMAPK1TXNRD1 | |
| SCHEMBL29064672 | 0.81 | TXNRD1 (0.37) | ALDH1A1KDM4EKMT2AMAPTMAPK1 | |
| SCHEMBL29064664 | 0.80 | TXNRD1 (0.39) | ALDH1A1MAPTMAPK1L3MBTL1TXNRD1 | |
| SCHEMBL16470758 | 0.79 | MAOA (0.38) | ALDH1A1KDM4EKMT2AMAOAMAPT | |
| SCHEMBL16469751 | 0.79 | MAPT (0.41) | ALDH1A1KDM4EKMT2AMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-116265460-B | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-116265460-A | Thiazole methyl pyridine amine compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |