SCHEMBL653107

SCHEMBL653107

CC(C)(C)N(C(=O)O)c1ccc(-c2ccsc2)cc1N

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.49
ACMSD Q8TDX5 1/20 0.43
HDAC1 Q13547 3/20 0.40
CHEK2 O96017 6/20 0.38
IKBKB O14920 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ERN1 O75460 1/20 0.37
BACE1 P56817 1/20 0.36
CHEK1 O14757 1/20 0.36
NR4A2 P43354 1/20 0.34
PTPRC P08575 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650663 0.82 MAPT (0.45) ACMSDHDAC1IKBKBALDH1A1MAPT
SCHEMBL650413 0.79 KCNH2 (0.51) KCNH2HDAC1
SCHEMBL651516 0.79 HDAC1 (0.53) KCNH2HDAC1CHEK2
SCHEMBL29064836 0.74 MKNK1 (0.46) HDAC1
SCHEMBL1512084 0.73 KEAP1 (0.42) HDAC1ALDH1A1MAPT
SCHEMBL653154 0.71 HDAC1 (0.45) KCNH2HDAC1CHEK2ALDH1A1MAPT
SCHEMBL17507930 0.71 ALDH1A1 (0.51) ALDH1A1MAPTCHEK1
SCHEMBL22637598 0.70 GAA (0.37) ALDH1A1MAPT
SCHEMBL27484057 0.69 KCNH2 (0.47) KCNH2ACMSDHDAC1CHEK2IKBKB
SCHEMBL247809 0.69 KDM4E (0.38) HDAC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4461867-A CONTAINING A DIORGANOCYCLOPOLYSILOXANE COMPOUND GENERAL ELECTRIC COMPANY (US) 1984-07-24 US claimed
JP-61064753-A None JP disclosed
JP-61034062-A None JP disclosed
JP-62295958-A None JP disclosed
JP-62096562-A None JP disclosed
JP-55127460-A None JP disclosed
JP-56095923-A None JP disclosed
US-20240067835-A1 POLYSILOXANE-BASED FOULING CONTROL COATING SYSTEMS HEMPEL A/S (DK) 2024-02-29 US disclosed
US-11787953-B2 Polysiloxane-based fouling control coating systems HEMPEL A/S (DK) 2023-10-17 US disclosed
CN-115846179-A Method for producing an antifouling coating system 汉伯公司 2023-03-28 CN disclosed
US-4467063-A N-SILYL-SUBSTITUTED IMIDAZOLE GENERAL ELECTRIC COMPANY (US) 1984-08-21 US disclosed
EP-0113849-A2 Alcoxy-functional one-component R.T.V. silicone rubber compositions GENERAL ELECTRIC COMPANY (US) 1984-07-25 EP disclosed
EP-0110251-A2 Process for producing alkoxy-terminated polysiloxanes GENERAL ELECTRIC COMPANY (US) 1984-06-13 EP disclosed
US-4395526-A SILANE SCAVENGER GENERAL ELECTRIC COMPANY (US) 1983-07-26 US disclosed
WO-1983000156-A1 ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING GEN ELECTRIC (US) 1983-01-20 WO disclosed
EP-0069256-A2 One package, stable, moisture curable, polyalkoxy-terminated organopolysiloxane compositions and method for making GENERAL ELECTRIC COMPANY (US) 1983-01-12 EP disclosed
EP-0050453-A1 An oil-resistant gasket material and packing material Toray Silicone Company Limited (JP) 1982-04-28 EP disclosed
JP-S5695923-A COLD CURING ORGANOPOLYSLOXANE COMPOSITION SHIN ETSU CHEM CO LTD 1981-08-03 JP disclosed
JP-S55127460-A ROOM TEMPERATURE VULCANIZING COMPOSITION SHIN ETSU CHEM CO LTD 1980-10-02 JP disclosed
JP-S06134062-A 0001-01-01 JP disclosed