Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24035931 | 0.86 | MAOA (0.42) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL13999812 | 0.85 | RAB9A (0.56) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL1691535 | 0.83 | MAOA (0.47) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL13999768 | 0.82 | L3MBTL1 (0.44) | ACHEALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL24036136 | 0.81 | MAOA (0.44) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL15156713 | 0.79 | MAOA (0.46) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL2079452 | 0.74 | RAB9A (0.54) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL2115643 | 0.73 | MAOA (0.47) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL29598578 | 0.73 | MAOA (0.47) | MAOAACHEMAPTNPC1RAB9A | |
| SCHEMBL14656020 | 0.72 | ACHE (0.64) | MAOAACHEMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4149459-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |