SCHEMBL29066009

SCHEMBL29066009

FC(F)C(F)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
HIF1A Q16665 4/20 0.46
MAPK1 P28482 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
LMNA P02545 3/20 0.44
CYP2A6 P11509 1/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
ADRB2 P07550 1/20 0.44
IDO1 P14902 4/20 0.41
CYP19A1 P11511 3/20 0.41
TDO2 P48775 3/20 0.41
CNR1 P21554 2/20 0.39
CYP3A4 P08684 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29248173 0.97 TSHR (0.44) TSHRHIF1AMAPK1TDP1LMNA
Hydrochloric Acid SCHEMBL29248251 0.95 IDO1 (0.43) TSHRHIF1AMAPK1TDP1LMNA
Hydrochloric Acid SCHEMBL29248199 0.95 IDO1 (0.43) TSHRHIF1AMAPK1TDP1LMNA
SCHEMBL7670364 0.85 PGK1 (0.35)
SCHEMBL9470689 0.77 LMNA (0.50) TSHRHIF1AMAPK1TDP1LMNA
SCHEMBL17816190 0.77 TSHR (0.50) TSHRHIF1AMAPK1TDP1LMNA
SCHEMBL20187508 0.75 ADRB2 (0.48) TSHRHIF1AMAPK1TDP1LMNA
SCHEMBL31065350 0.74 TSHR (0.42) TSHRHIF1AMAPK1TDP1LMNA
SCHEMBL3973319 0.72 ESR1 (0.50) TSHRHIF1ATDP1LMNAHPGD
SCHEMBL21875043 0.72 IDO1 (0.35) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535285-A Photocatalytic benzyl position C (sp 3 ) Method for functionalization of Cl bonds and use thereof 中国科学院理化技术研究所 2023-08-04 CN disclosed