Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | TDO2 | P48775 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662302 | 0.83 | PGK1 (0.38) | IDO1TDO2TRPV4 | |
| SCHEMBL17816190 | 0.81 | TSHR (0.50) | LMNATSHRMAPK1HIF1ATDP1 | |
| Bromide SCHEMBL9813321 | 0.79 | NOTUM (0.37) | TRPV4 | |
| SCHEMBL29066009 | 0.77 | TSHR (0.46) | LMNATSHRMAPK1HIF1ATDP1 | |
| SCHEMBL29200286 | 0.77 | TSHR (0.46) | LMNATSHRMAPK1HIF1ATDP1 | |
| SCHEMBL16425762 | 0.77 | ADRB2 (0.56) | LMNATSHRMAPK1HIF1ATDP1 | |
| SCHEMBL21994332 | 0.77 | TSHR (0.46) | LMNATSHRMAPK1HIF1ATDP1 | |
| SCHEMBL4547938 | 0.75 | TYR (0.46) | LMNAMAPK1HIF1AHPGDADRB2 | |
| SCHEMBL14501582 | 0.75 | TRPV4 (0.35) | TSHRMAPK1HIF1ATDP1TRPV4 | |
| SCHEMBL14501581 | 0.75 | TSHR (0.50) | TSHRMAPK1HIF1ATDP1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185473-B | Preparation method of florfenicol intermediate fluoromethylsulfone oxazole | 山东国邦药业有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-113185473-A | Preparation method of florfenicol intermediate fluoromethylsulfone oxazole | 山东国邦药业有限公司 | 2021-07-30 | — | — | CN | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| WO-2015103137-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | WO | claimed |
| EP-3632892-B1 | METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2024-07-31 | — | — | EP | disclosed |
| CN-110799490-B | 3-arylpropionamide compound and method for producing 3-arylpropionate compound | 住友化学株式会社 | 2023-05-02 | — | — | CN | disclosed |
| US-11376260-B2 | Serine/threonine kinase inhibitors | GENENTECH, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| CN-113185473-B | Preparation method of florfenicol intermediate fluoromethylsulfone oxazole | 山东国邦药业有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113185473-B | Preparation method of florfenicol intermediate fluoromethylsulfone oxazole | 山东国邦药业有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113185473-A | Preparation method of florfenicol intermediate fluoromethylsulfone oxazole | 山东国邦药业有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-101238602-A | Electrode electrolyte for use in solid polymer fuel cell | JSR CORP (JP) | 2008-08-06 | — | — | CN | disclosed |
| CN-101223208-A | Nitrogenated aromatic compound, process for production of the same, polymer, and proton conductive membrane | JSR CORP (JP) | 2008-07-16 | — | — | CN | disclosed |
| CN-1981352-A | Electrochemical capacitor | JSR CORP (JP) | 2007-06-13 | — | — | CN | disclosed |
| US-5233105-A | Fluorination using hydrogen fluoride | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0425887-A2 | Process for halogen-fluor exchange in organic compounds and catalysts therefor | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0076718-B1 | PROCESS FOR THE HALOGENATION OF METADIHALOGENOBENZENES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-12 | — | — | EP | disclosed |
| EP-0076718-A1 | Process for the halogenation of metadihalogenobenzenes | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11376260-B2 | Serine/threonine kinase inhibitors | MAP3K1, MAP3K4, MAP4K2 | LMNA 2948/4885TSHR 2044/4885MAPK1 12/4885 |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | TTBK1, MAP3K1, TNNI3K | LMNA 1573/4885TSHR 2352/4885MAPK1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.