Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 17/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527163 | 1.00 | THRA (0.48) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL29066205 | 0.88 | THRB (0.39) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL29066176 | 0.86 | THRA (0.47) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29527065 | 0.86 | THRA (0.47) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29632803 | 0.84 | THRB (0.52) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL29527000 | 0.82 | THRB (0.39) | THRATHRBL3MBTL1 | |
| SCHEMBL29066188 | 0.79 | FFAR1 (0.40) | — | |
| SCHEMBL29527699 | 0.79 | FFAR1 (0.40) | — | |
| SCHEMBL23663177 | 0.77 | THRA (0.61) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL29066224 | 0.75 | SMN1; SMN2 (0.38) | L3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |