SCHEMBL29066176 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	THRA	P10827	18/20	0.47

▸	THRB	P10828	18/20	0.47

▸	CYP2C9	P11712	2/20	0.47

▸	CYP2C8	P10632	1/20	0.47

▸	UGT1A1	P22309	1/20	0.35

▸	ABCG2	Q9UNQ0	1/20	0.35

▸	SLCO1B1	Q9Y6L6	1/20	0.35

▸	TYK2	P29597	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29527065	1.00	THRA (0.47)	THRATHRBCYP2C9CYP2C8UGT1A1
SCHEMBL29527163	0.86	THRA (0.48)	THRATHRBCYP2C9UGT1A1ABCG2
SCHEMBL29066161	0.86	THRA (0.48)	THRATHRBCYP2C9UGT1A1ABCG2
SCHEMBL29066205	0.84	THRB (0.39)	THRATHRBCYP2C9UGT1A1ABCG2
SCHEMBL29526700	0.84	THRB (0.54)	THRATHRBCYP2C9CYP2C8UGT1A1
SCHEMBL29066213	0.84	THRB (0.54)	THRATHRBCYP2C9CYP2C8UGT1A1
SCHEMBL29527151	0.81	THRB (0.49)	THRATHRBCYP2C9CYP2C8
SCHEMBL29066209	0.81	THRB (0.49)	THRATHRBCYP2C9CYP2C8
SCHEMBL24450109	0.81	THRA (0.51)	THRATHRBCYP2C9CYP2C8UGT1A1
SCHEMBL29527043	0.81	THRA (0.52)	THRATHRBCYP2C9CYP2C8UGT1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116710443-A	2-pyridones as thyroid hormone receptor modulators	阿利戈斯治疗公司	2023-09-05	—	—	CN	disclosed