Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP1 | P63208 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | FPR3 | P25089 | 5/20 | 0.44 |
| ▸ | FPR2 | P25090 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30850465 | 0.86 | CKS1B (0.49) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL1433076 | 0.84 | MAPT (0.49) | CKS1BSKP1SKP2FPR3FPR2 | |
| SCHEMBL30850514 | 0.82 | MAPT (0.50) | CKS1BSKP1SKP2NPC1RAB9A | |
| SCHEMBL24329996 | 0.81 | TMEM97 (0.48) | CKS1BSKP1SKP2FPR3FPR2 | |
| SCHEMBL1998123 | 0.78 | CKS1B (0.53) | CKS1BSKP1SKP2SUV39H2MALT1 | |
| SCHEMBL15092378 | 0.78 | AAK1 (0.48) | CKS1BSKP1SKP2SUV39H2MALT1 | |
| SCHEMBL9100684 | 0.78 | CKS1B (0.52) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL24257374 | 0.77 | TDP1 (0.48) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL1065312 | 0.77 | CA2 (0.55) | FPR3FPR2NPC1RECQLRAB9A | |
| SCHEMBL31687500 | 0.76 | SIGMAR1 (0.58) | FPR3FPR2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116723839-A | Tricyclic heterobifunctional compounds for degrading target proteins | C4医药公司 | 2023-09-08 | — | — | CN | disclosed |