Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP1 | P63208 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24413753 | 0.85 | TDP1 (0.48) | CKS1BSKP1SKP2TDP1MEN1 | |
| SCHEMBL8747512 | 0.84 | KMT2A (0.50) | CKS1BSKP1SKP2TDP1MEN1 | |
| SCHEMBL9363322 | 0.84 | TDP1 (0.49) | CKS1BSKP1SKP2TDP1MEN1 | |
| SCHEMBL24257374 | 0.83 | TDP1 (0.48) | CKS1BSKP1SKP2TDP1MEN1 | |
| SCHEMBL24413752 | 0.82 | MALT1 (0.49) | CKS1BSKP1SKP2TDP1BCHE | |
| SCHEMBL4600182 | 0.81 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL8993992 | 0.80 | SMN1; SMN2 (0.42) | BCHEMEN1KMT2AUSP2CYP3A4 | |
| SCHEMBL13415823 | 0.79 | MTNR1A (0.66) | BCHEMTNR1AMTNR1BUSP2CNR1 | |
| SCHEMBL8354855 | 0.79 | CYP3A4 (0.52) | TDP1MEN1GAAKMT2AMALT1 | |
| SCHEMBL24974709 | 0.79 | MALT1 (0.51) | CKS1BSKP1SKP2TDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474431-B1 | Amphiphilic compounds for sequential monolayer deposition | ICI PLC (GB) | 1996-03-06 | — | — | EP | disclosed |
| US-5275924-A | Non-centrosymmetric; hydrophobic; chromophores | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |