Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP1 | P63208 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257374 | 0.91 | TDP1 (0.48) | CKS1BSKP1SKP2CA1CA2 | |
| SCHEMBL29066264 | 0.86 | CKS1B (0.49) | CKS1BSKP1SKP2SUV39H2CA1 | |
| SCHEMBL1998123 | 0.83 | CKS1B (0.53) | CKS1BSKP1SKP2SUV39H2CA1 | |
| SCHEMBL30850514 | 0.82 | MAPT (0.50) | CKS1BSKP1SKP2SUV39H2LMNA | |
| SCHEMBL15707597 | 0.80 | CYP1A1 (0.41) | CKS1BSKP1SKP2SUV39H2CA1 | |
| SCHEMBL29024510 | 0.79 | ALDH1A1 (0.45) | TDP1LMNASLC22A2SLC22A1ALDH1A1 | |
| SCHEMBL15092378 | 0.78 | AAK1 (0.48) | CKS1BSKP1SKP2SUV39H2CA1 | |
| SCHEMBL9100684 | 0.78 | CKS1B (0.52) | CKS1BSKP1SKP2CA1CA2 | |
| SCHEMBL23329003 | 0.77 | GBA1 (0.42) | TDP1ALDH1A1TSHRMAPK1MAOA | |
| SCHEMBL8993963 | 0.77 | MMP14 (0.38) | TDP1LMNAALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024244888-A1 | 9-MEMBERED HETEROARYL COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING 9-MEMBERED HETEROARYL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东弘烨医药科技有限公司 | 2024-12-05 | — | — | WO | disclosed |
| WO-2024102970-A1 | COMPOUNDS FOR MODULATING SYK ACTIVITY AND E3 UBIQUITIN LIGASE ACTIVITY | Kronos Bio, Inc. (US) | 2024-05-16 | — | — | WO | disclosed |