Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.53 |
| ▸ | RAB9A | P51151 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29066483 | 1.00 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL29066493 | 0.80 | MAPT (0.61) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL29066494 | 0.80 | MAPT (0.61) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL29066482 | 0.77 | RAB9A (0.48) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29066479 | 0.77 | RAB9A (0.48) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29066490 | 0.76 | KDM4E (0.60) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL30421200 | 0.76 | KDM4E (0.60) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29066492 | 0.76 | KDM4E (0.60) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29066480 | 0.75 | MAPT (0.48) | NPC1RAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL30421177 | 0.75 | MAPT (0.48) | NPC1RAB9AMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283822-A | Thiazole and imidazo [1,2-a ] pyridine acylhydrazone compounds and application thereof | 西北农林科技大学 | 2023-06-23 | — | — | CN | disclosed |