Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476692 | 1.00 | LMNA (0.42) | LMNAMAPK1HTTRAB9ATPMT | |
| SCHEMBL25318666 | 0.94 | LMNA (0.40) | LMNAMAPK1HTTRAB9ATPMT | |
| SCHEMBL30903838 | 0.81 | RAB9A (0.49) | HTTRAB9APKM | |
| SCHEMBL30903840 | 0.79 | CA12 (0.41) | LMNAMAPK1HTTRAB9APTGS2 | |
| SCHEMBL29475542 | 0.78 | MLYCD (0.33) | TUBB1 | |
| SCHEMBL25320728 | 0.78 | MLYCD (0.33) | TUBB1 | |
| SCHEMBL30903834 | 0.78 | MEN1 (0.47) | LMNARAB9AKMT2A | |
| SCHEMBL1458628 | 0.78 | LMNA (0.58) | LMNAMAPK1HTTRAB9ATPMT | |
| SCHEMBL22466074 | 0.77 | RAB9A (0.47) | HTTRAB9APKM | |
| SCHEMBL29375615 | 0.77 | RAB9A (0.47) | HTTRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |