Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18628807 | 0.86 | TTR (0.51) | TTRGAAAURKAAURKBCA12 | |
| SCHEMBL27467770 | 0.85 | GAA (0.54) | TTRGAACA12CA1CA2 | |
| Sulfuric Acid SCHEMBL6417779 | 0.84 | TTR (0.42) | TTRGAACA12CA1CA2 | |
| SCHEMBL7597804 | 0.83 | AURKA (0.41) | TTRGAAAURKAAURKBCA2 | |
| SCHEMBL4788421 | 0.83 | CA2 (0.55) | TTRGAACA12CA1CA2 | |
| SCHEMBL18628809 | 0.83 | TTR (0.49) | TTRGAAAURKAAURKBCA12 | |
| SCHEMBL27731651 | 0.81 | GAA (0.41) | TTRGAACA12CA1CA2 | |
| SCHEMBL2052228 | 0.81 | GABRA1 (0.45) | TTRCYP1A2HSD17B10MYCLMNA | |
| SCHEMBL16713744 | 0.80 | TTR (0.46) | TTRCA12CA2CA9CYP1A2 | |
| SCHEMBL1115550 | 0.80 | TTR (0.46) | TTRCA12CA2CA9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261253-A2 | Antibodies directed to Clostridium difficile | NEUTEC PHARMA PLC (GB) | 2010-12-15 | — | — | EP | disclosed |
| EP-1613655-B1 | CLOSTRIDIUM DIFFICILE FOCUSSED ANTIBODIES | NEUTEC PHARMA PLC (GB) | 2010-08-11 | — | — | EP | disclosed |
| US-20070071763-A1 | Clostridium difficile focussed antibodies | NEUTEC PHARMA PLC (GB) | 2007-03-29 | — | — | US | disclosed |
| US-20060233812-A1 | Focussed antibody technology | NEUTEC PHARMA LIMITED (GB) | 2006-10-19 | — | — | US | disclosed |
| EP-1613655-A1 | CLOSTRIDIUM DIFFICILE FOCUSSED ANTIBODIES | NEUTEC PHARMA PLC (GB) | 2006-01-11 | — | — | EP | disclosed |
| EP-1415002-B1 | FOCUSSED ANTIBODY TECHNOLOGY | NEUTEC PHARMA PLC (GB) | 2005-02-02 | — | — | EP | disclosed |
| WO-2004094474-A1 | CLOSTRIDIUM DIFFICILE FOCUSSED ANTIBODIES | NEUTEC PHARMA PLC (GB) | 2004-11-04 | — | — | WO | disclosed |
| EP-1415002-A2 | FOCUSSED ANTIBODY TECHNOLOGY | Neutec Pharma PLC (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003052416-A2 | FOCUSSED ANTIBODY TECHNOLOGY | NEUTEC PHARMA PLC (GB) | 2003-06-26 | — | — | WO | disclosed |